NL-OMON45357已完成4 期
GLP-1 for bridging of hyperglycaemia during cardiac surgery: a randomized controlled trial - The GLOBE trial
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 274
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •* Adult patients, aged 18-80 years (inclusive),
- •* No known diabetes mellitus, or
- •* Known diabetes mellitus type 2 on oral glucose lowering medication, diet or total daily insulin dose *0.5 IU/kg
- •* Scheduled for an elective cardiac surgical procedure.
- •* Informed consent obtained before any trial-related activities are carried out.
排除标准
- •* Diabetes mellitus type 1
- •* Emergency surgery
- •* Receiving oral corticosteroid therapy
- •* History of pancreatic surgery or acute or chronic pancreatitis
- •* Personal or family history of medullary thyroid cancer (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
- •* Heart failure NYHA class IV
- •* Serum-creatinine * 133 *mol l-1 for males and * 115 *mol l-1 for females
- •* Female of child-bearing potential who is pregnant, breast-feeding or intend to become pregnant or is not using adequate contraceptive methods
- •* Current treatment with GLP-1 analogues
- •* Known or suspected allergy to trial products or other drugs in the same class
研究者
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