Comparison of the Efficacy of Ultrasound-Guided Phenol Block and Corticosteroid-Local Anesthetic Block Applied to the Genicular Nerve in Patients With Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- Numeric Rating Scale (NRS)
研究概览
简要总结
There are different neurolysis methods. Aim of this study is to compare two different methods, phenol block and corticosteroid local anesthetic block.
详细描述
Knee osteoarthritis is one of most frequent reason of knee pain. There are different treatment methods such as analgesic drug treatment, physical therapy techniques, intraarticular injections and neurolysis techniques. In this study, we will compare neurolysis techniques these are phenol block and corticosteroid local anesthetic block.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with knee osteoarthritis must have pain at least 6 months
- •NRS score of knee pain equal or more than 5
- •At least grade 3 in Kellgren-Lawrence grading scale
- •Non responsive to life style change, weight control, exercises program, medical treatment and the other conservative treatments (physical therapy, intraarticular injections)
- •Decreasing at NRS score more than %50 after diagnostic block
- •Those who accept the consent form
排除标准
- •Patients who have acute knee injury
- •Surgery history in knee
- •Connective tissue disease that affect knee
- •Injection story in last 3 months
- •Psychiatric or neurologic diseases that affect study
- •Septic arthritis, active local or systemic infection
- •Coagulopathy
- •Pregnancy
- •Allergic reaction
研究组 & 干预措施
Phenol block group
干预措施: Phenol (Drug)
Corticosteroid and local anesthetic
干预措施: Celestone (Drug)
Corticosteroid and local anesthetic
干预措施: Lidocain (Drug)
结局指标
主要结局
Numeric Rating Scale (NRS)
时间窗: Before the intervention, 4 weeks after the intervention and 3 months later
Average knee pain is assessed using an 11-point NRS with terminal descriptors of no pain (score 0) and extreme pain (score 10).
次要结局
- Frequency of analgesic usage(Before the intervention, 4 weeks after the intervention and 3 months later)
- Sixt Minute Walk Test (6MWT)(Before the intervention, 4 weeks after the intervention and 3 months later)
- Western Ontario and McMaster Universities Arthritis Index (WOMAC)(Before the intervention, 4 weeks after the intervention and 3 months later)
- Patient Global Impression of Change (PGIC)(4 weeks after the intervention and 3 months later)
- The Timed-Up and Go test(Before the intervention, 4 weeks after the intervention and 3 months later)
研究者
Rabia Layık
assist. dr.
Gaziler Physical Medicine and Rehabilitation Education and Research Hospital