Executive Functioning and Mindfulness in Adults With ADHD Imaging
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 主要终点
- change from baseline in blood-oxygenation-level-dependent (BOLD) fMRI signal
研究概览
简要总结
The main purpose of this study is to evaluate changes in brain functioning using an MRI machine following mindfulness meditation training.
详细描述
The broad objective of this proposal is to identify functional neuroanatomical correlates of changes in executive brain functioning prior to and following an 8-week, group-based mindfulness meditation intervention within a group of 10 adults diagnosed with Attention-deficit/hyperactivity disorder (ADHD). Another group of 10 adults diagnosed with ADHD will be placed in the waitlist condition.
Our primary hypothesis is that adults with ADHD in the treatment group will exhibit improved performance on a series of executive functioning tasks and that exposure to task stimuli will correspond to changes in neural functioning following an 8-week, group-based mindfulness intervention. Brain responses will be measured using blood-oxygenation-level-dependent (BOLD) fMRI signal in brain regions associated with emotional and executive processes prior to and following treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ages 18-50 years
- •meet DSM-IV criteria for ADHD
- •intellectual functioning ≥ 80 as assessed by an IQ screener
- •generally healthy (i.e., no major medical problems)
排除标准
- •major medical condition that would make participation unsafe (e.g., have pacemaker or other metallic implant), uncomfortable (e.g., chronic pain)
- •claustrophobic, or abnormally afraid of closed-in places
- •current drug use
结局指标
主要结局
change from baseline in blood-oxygenation-level-dependent (BOLD) fMRI signal
时间窗: baseline and 8-weeks
Participants will be scanned prior to and following an 8-week group-based mindfulness meditation intervention
次要结局
未报告次要终点