Focal Adhesion Kinase Expression in Pediatric Renal Tumors
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- FAK expression in pediatric renal tumors
研究概览
简要总结
This laboratory study is looking into biomarkers in samples from younger patients with kidney cancer. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat cancer.
详细描述
PRIMARY OBJECTIVES:
I. To determine whether focal adhesion kinase (FAK) is expressed and if FAK is phosphorylated in pediatric renal tumors.
OUTLINE:
Archived tumor tissue samples are analyzed for FAK expression by immunohistochemistry (IHC). IHC staining is compared in normal renal tissue, Wilms tumor (routine and anaplastic), malignant rhabdoid tumor of the kidney, clear cell sarcoma of the kidney, and mesoblastic nephroma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Formalin-fixed, paraffin-embedded tissue samples from patients diagnosed with the following renal tumors:
- •Anaplastic Wilms tumor
- •Malignant rhabdoid tumor of the kidney
- •Clear cell sarcoma of the kidney
- •Mesoblastic nephroma
排除标准
- 未提供
结局指标
主要结局
FAK expression in pediatric renal tumors
时间窗: Baseline
次要结局
未报告次要终点