Platelet Function During Extracorporeal Membrane Oxygenation in Adult Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 33
- 试验地点
- 2
- 主要终点
- Changes in platelet function
研究概览
简要总结
The primary aim is to describe platelet function in adult patients treated with extracorporeal membrane oxygenation (ECMO). A clarification of the platelet function in these critically ill patients contributes to an understanding of the mechanisms underlying their coagulopathy.
The present study is a substudy to the study entitled; "Coagulopathy During Extracorporeal Membrane Oxygenation" (pending Clinical Trial ID number).
详细描述
The knowledge of platelet function during extracorporeal membrane oxygenation (ECMO) remains sparse. In the present study, the aim is to investigate platelet function in adult patients treated with ECMO using flow cytometry. The investigators hypothesize that platelet function increases from day 1 to day 3 in patients treated with ECMO. The secondary aim is to investigate the association between platelet function and the incidence of bleeding episodes and thrombosis during ECMO treatment.
The present study is a substudy to the study entitled; "Coagulopathy During Extracorporeal Membrane Oxygenation" (pending Clinical Trial ID number).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Treatment with veno-venous or veno-arterial ECMO
- •Age ≥18 years
排除标准
- •ECMO treatment initiated post-operatively
结局指标
主要结局
Changes in platelet function
时间窗: Platelet function measured day 1 and day 3 on ECMO
Platelet function on day 3 compared with day 1 on ECMO. Measured by flow cytometry
次要结局
- Changes in platelet aggregation(Platelet function measured every morning from day 1 to day 8 on ECMO (except weekends).)
- Immature platelet count(Measured every morning from day 1 to day 8 on ECMO (except weekends))
- Platelet count(Measured every morning from day 1 to day 8 on ECMO (except weekends))