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临床试验/NCT07584525
NCT07584525招募中3 期

Treatment With Dexamethasone in Patients With Tick-borne Encephalitis: Randomized Clinical Trial

University Medical Centre Ljubljana1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2024年5月3日最近更新:
适应症

试验速览

阶段
3 期
状态
招募中
入组人数
200
试验地点
1

研究概览

简要总结

The purpose of this study is to investigate the efficacy of dexamethasone in patients with tick-borne encephalitis.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age 18 years or older and
  • clinical signs and symptoms of meningoencephalitis or meningomyelitis and
  • cerebrospinal pleocytosis and
  • serological confirfmation of tick-borne encephalitis virus infection

排除标准

  • pregnancy or
  • severe neurological impairment befor tick-borne encephalitis or
  • systemic corticosteroid treatment in the past 30 days or
  • allergy to corticosteroids or
  • immunosuppresive condition or therapy such as HIV with CD4 < 200/ml, organ or bone marrow transplant, receiving chemotherapy, radiotherapy or any other immunosuppresive therapy, primary immunodeficiency, hematological maliganncy or
  • ventricular shunt or
  • endoscopically documented peptic gastric ulcer in the past six months or gastrointestinal bleeding with hemoglobin drop ≥ 20 units or
  • uncontrolled diabetes with hyperglicemia or
  • antiviral therapy with rilpivirin

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Daša Stupica

MD, PhD, assoc. prof.

University Medical Centre Ljubljana

研究点 (1)

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