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临床试验/NCT05659758
NCT05659758已完成不适用

Is Effective Preoxygenation in Elderly Patients Related to Position?

Ankara City Hospital Bilkent1 个研究点 分布在 1 个国家目标入组 156 人开始时间: 2022年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
156
试验地点
1
主要终点
Time ETO2 85%

研究概览

简要总结

The purpose of this study is to investigate the effect of the head-up position of 20 and 30 degrees on the ETO2 reaching time of 85% and the desaturation time of 92% after intubation in elderly patients compared to the supine position.

详细描述

Patients will be randomized into 3 groups. The patients will lay in the supine position, in the control group and 20 and 30 degrees head up position in other two groups. Each patient will be preoxygenated with well fitting anaesthesia face mask with FiO2 of 100% at least 6L of flow until the ETO2 reaches concentration of 85%. The angle (20 or 30 degrees) formed by the patients' bodies (hips and feet parallel to the ground, lifting the back from the ground plane) with the ground will be measured with a spirit level, angle meter, and confirmed with a smartphone application. The time to reach ETO2 85% by starting preoxygenation in patients will be measured and recorded with a stopwatch. When the target is reached, anesthesia induction will be performed and the patients will be intubated. After the start of the intubation attempt, the stopwatch will be started again, after intubation, the patient will be ventilated with a balloon once and the location of the tube will be confirmed, the circuit will be separated and SpO2 will be expected to go down to the level of 92 % and recorded during this time.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
65 Years 至 95 Years(Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age above 65 years

排除标准

  • •heart failure
  • •uncooperative
  • •patients refusing well fitting face mask before reaching EtO2 85%
  • •chronic lung disease
  • •anemia (hb<8gr/dl)
  • •neurological sequela

研究组 & 干预措施

control

Other

patients will be preoxygenated in supine position

干预措施: Head up positioning during preoxygenation (Procedure)

20 degree

Experimental

patients will be preoxygenated in 20 degrees head up position

干预措施: Head up positioning during preoxygenation (Procedure)

30 degree

Experimental

patients will be preoxygenated in 30 degrees head up position

干预措施: Head up positioning during preoxygenation (Procedure)

结局指标

主要结局

Time ETO2 85%

时间窗: Time between placement of face mask and end tidal oxygen concentration reaches 85 %

Time to reach ETO2 85 %

次要结局

  • Desaturation time(Time between initiation laryngoscopy for endotracheal intubation and peripheral oxygen saturation reaches 92 % measured by pulseoxymeter)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Namik ozcan

Associate Professor of Anesthesiology and Reanimation, Principle Investigator

Ankara City Hospital Bilkent

研究点 (1)

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