NL-OMON44254招募中不适用
on-invasive assessment of lung remodeling in patients with idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) using [11C]-Nintedanib or [18F]-FLT PET imaging. - Imaging the primary disease process in IPF and PAH
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- •1. Diagnosis of IPF, according to ATS/ERS guidelines (ref Raghu AJRCCM 2011)
- •Diagnosis of PAH, according to ESC/ERS guidelines (ref: Galie ERJ 2015)
- •Unaffected BMPR2 mutation carrier
- •Normal control subjects
- •2. Age >18 and <80 years
排除标准
- •- Claustrophobia
- •- Inability to provide informed consent
- •- In case of IPF patients: pulmonary hypertension suspected by echocardiography or proven by right heart
- •catheterization
- •- In case of PAH patients: TLC < 70%pred or radiographic evidence of interstitial lung disease
- •- In case of BMPR2 mutation carriers and normal control subjects, one or more of the following: abnormal
- •spirometry, TLC < 70%, echocardiographic evidence of pulmonary hypertension
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