Intraoperative Pain During Extraction of Maxillary Primary Molars Using Artpharma Versus Artinibsa in Children After Infiltration Technique: a Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 130
- 主要终点
- Intraoperative pain.
研究概览
简要总结
The aim of this study is to assess Intraoperative pain for extraction of Maxillary primary molars using Artpharma Versus Artinibsa in children during infiltration technique.
详细描述
Articaine is used for pain control Like other local anesthetic drugs, articaine causes a temporary and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.This local anesthesia was first synthesized by Rusching in 1969, and carried to the market in Germany by Hoechst AG, a life-sciences German company, under the brand name Ultracain ,it entered clinical practice in Germany in 1976. The name was changed in 1984, the year it was released in Canada. It then entered the United Kingdom in 1998, the United States in 2000 and Australia in 2005. At this time, articaine is available as a 4% solution containing 1:100, 000 or 1:200, 000 adrenaline. Articaine has been widely used in dental surgery.It started to use carticaine around 1977.In dentistry has been investigated widely. Articaine is a unique amide LA in that it contains a thiophene, instead of a benzene ring.The thiophene ring allows greater lipid solubility and effectiveness as a greater portion of an administered dose can enter neurons
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
Single (Participant) single ( participant ) because the two interventions used in this trial are easily recognized by the investigator but the participant and the statistician will be blinded.
入排标准
- 年龄范围
- 6 Years 至 9 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children aged 6-9 years.
- •Children with maxillary primary molars indicated for extraction.
排除标准
- •Children with medical conditions.
- •Uncooperative children.
- •Parents or guardians who refuse participating in the study.
结局指标
主要结局
Intraoperative pain.
时间窗: immediate
Intraoperative pain: is measuring by using Wong Baker visual analogue scale and measuring unite is Scale (0-10).
次要结局
- Onset of anesthesia.(Immediate)
- Pain during injection(success rate).(immediate)
- The sensation after injection.(Immediate)
研究者
Hafedha Hashem Abdullah
Principle Investigator
Cairo University