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临床试验/NCT01312649
NCT01312649已完成不适用

Feeling of Being in Control of One's Own Action: Which Mechanisms in Healthy Volunteers and in Mental Diseases

University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 198 人开始时间: 2011年4月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
198
试验地点
1

研究概览

简要总结

The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). These symptoms are mainly encountered in patients with schizophrenia, and the investigators will distinguish patients with schizophrenia with or without this symptom together with patients with bipolar disorder. Based on the investigators previous studies, this project will help to determine the role of two elementary mechanisms in the ability to feel in control of voluntary actions: (1) the processing of the sensory consequences of action, and (2) the ability to build mental representations for sequenced actions.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with schizophrenia or bipolar disorders (criteria DSM IV) or healthy controls matched with patients on age, sex and education level
  • 18-55 years old

排除标准

  • Past history affecting CNS
  • Invalidating sensory disorders
  • Intake of psychotropic drugs, except for patients
  • Intake of benzodiazepines

研究组 & 干预措施

Arm 1

Experimental

Healthy volunteers

干预措施: Experimental psychology methods (computer tests) (Behavioral)

Arm 2

Experimental

Schizophrenia with history of delusions of control

干预措施: Experimental psychology methods (computer tests) (Behavioral)

Arm 3

Experimental

Schizophrenia without history of delusions of control

干预措施: Experimental psychology methods (computer tests) (Behavioral)

Arm 4

Experimental

Bipolar disorders

干预措施: Experimental psychology methods (computer tests) (Behavioral)

Arm 5

Active Comparator

Matched healthy controls

干预措施: Experimental psychology methods (computer tests) (Behavioral)

研究者

发起方
University Hospital, Strasbourg, France
申办方类型
Other
责任方
Sponsor

研究点 (1)

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