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临床试验/NCT01756014
NCT01756014Unknown不适用

Brain Function and Perfusion in Patients With Heart Failure

University Medical Center Groningen1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2012年1月最近更新:
适应症

试验速览

阶段
不适用
入组人数
45
试验地点
1
主要终点
Determinants of cerebral impairment

研究概览

简要总结

The investigators will evaluate the determinants of cerebral impairment in patients with non-ischemic heart failure compared to controls, and its relation to cognitive function. They hypothesize that patients with heart failure have impaired brain perfusion and hemodynamic factors are associated with cognitive dysfunction.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Determinants of cerebral impairment

时间窗: Baseline

Determinants of cerebral impairment in patients with heart failure compared to controls, where cerebral impairment is defined as decreased cognitive function and cerebral hypoperfusion

次要结局

  • Prevalence of cognitive impairment(Baseline)
  • Relation of cognitive impairment with local perfusion(Baseline)
  • Relation of cognitive impairment with the severity of heart failure(Baseline)
  • Relation of cognitive impairment with cardiac output(Baseline)
  • Relation of cognitive impairment with the severity of congestion(Baseline)
  • Relation of cognitive impairment with the decrease in cerebral perfusion(Baseline)
  • The difference of cognitive domains in above relations(Baseline)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

A.A.Voors

Prof. dr.

University Medical Center Groningen

研究点 (1)

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