Comparative study of Intra thecal 0.5% isobaric Ropivacaine versus 0.5% isobaric Levo bupivacaine in unilateral hernia surgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To compare duration of motor and sensory blockade of intrathecal 0.5% isobaric levobupivacaine with 0.5% isobaric ropivacaine
研究概览
简要总结
A comparative study of intrathecal 0.5% levobupivacaine versus 0.5% ropivacaine in unilateral inguinal hernia surgeries was proposed as a study to compare duration of motor and sensory blockade as primary objective. Secondary objective being to compare the onset time to maximum sensory and motor blockade and hemodynamic parameters and our hypothesis is that levobupivacaine has prolonged duration of sensory and motor blockade which is better for prolonged surgeries and ropivacaine has shorter duration of motor blockade which is preferred for faster recovery and early ambulation and hence the latter can be administered for daycare surgeries. It is also beneficial in context of decreasing the incidence of urinary retention .
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.ASA 1 & 2 patients 2.Scheduled for unilateral inguinal hernia surgeries.
排除标准
- •1.Patients not willing to participate in the study
- •Contra indications to spinal anaesthesia ( INR>1.3, platelet count <75000)
- •ASA 3,4 patients
- •Neurological diseases like multiple sclerosis, lumbar disc herniation etc...
- •Allergy to local anaesthetics.
结局指标
主要结局
To compare duration of motor and sensory blockade of intrathecal 0.5% isobaric levobupivacaine with 0.5% isobaric ropivacaine
时间窗: After giving spinal blood pressure and heart rate will be checked every one minute for 10 mins and every 5 mins for next 1 hour and then every 15 mins until the end of the surgery.Sensory and motor blockade will be assessed every 3 min for 15 min and every 10 min for 45 min,every 15 min for 90 min and finally 30 min thereafter until sensory block regress to S2 dermatome.
次要结局
- 1.onset of action(2.time to maximum sensory and motor blockade)