EUCTR2012-003125-24-IT进行中（未招募）不适用
Evaluation of platelet functional response in relation to the bioavailability of clopidogrel in patients with acute coronary syndromes without ST-segment elevation (NSTEACS).
A.O. UNIVERSITARIA INTEGRATA DI VERONA0 个研究点开始时间: 2012年9月21日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Subjects (aged 18 to 75 years) with non–ST-segment elevation ACS (NSTEACS) and GRACE risk score< 140. Patients included must have platelet count =450.000/mm3 at presentation
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 10
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 15
排除标准
- •-Cardiogenic shock at recruitment; - Refractory ventricular arhythmias;- Prior Transient Ischemic Attack or Stroke; -Active internal bleeding or history of bleeding diathesis;-Increased bleeding risk for:Propensity to bleed (e.g., recent trauma, recent surgery, recent or recurrent gastrointestinal bleeding, active peptic ulcer disease, or severe hepatic impairment); arteriovenous malformation, or aneurysm;concomitant use of medications that increase the risk of bleeding as warfarin and fibrinolytic therapy; chronic use of non-steroidal anti-inflammatory drugs [NSAIDS] different from aspirin; CABG; platelet count <100.000/mm3 at presentation; anemia (hemoglobin <10 g/dL) at presentation. - Treatment with clopidogrel during the previous 30 days; -BMI > o = 33; -Intolerance or allergy to aspirin or clopidogrel;-Severe illness with life expectancy less than 1 year;-Test positive for pregnancy (based on a urine or serum pregnancy test) at presentation;-Women who have given birth within the previous 90 d;-Any condition associated with poor treatment compliance, including alcoholism, mental illness (or -Treatment with psychotropic drugs), or drug dependence.- Women of childbearing age not using contraception;- Women during lactation;- Patients in emergency situations;- Subjects incapable of giving legal consent.
研究者
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