Comparison of perineural & intravenous magnesium sulphate as an adjuvant to levobupivacaine in ultrasound – guided supraclavicular brachial plexus block: A prospective randomized trial
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- To compare the onset of sensory & motor block
研究概览
简要总结
To compare analgesic efficacy between perineural and intravenous magnesium sulphate as an adjuvant to levobupivacaine in ultrasound-guided supraclavicular brachial plexus block
Group 1 perineural magnesium sulphate – patient will receive 0.5% levobupivacaine (24.5ml) with 250 mg of magnesium sulphate (0.5ml) total volume of 25ml in usg guided supraclavicular nerve block
Group 2 intravenous magnesium sulphate – patient will receive 0.5% levobupivacaine (24.5ml) with 0.5ml NS total volume of 25ml in usg guided supraclavicular nerve block plus 30 mg/kg iv magnesium sulphate
Primary objective
•To compare the onset of sensory and motor block
Secondary objective
•To compare the duration of analgesia
•To compare the requirement of rescue analgesic in the postoperative period
•To compare the side effects (if any)
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Age between
- •60 years 2.Both sexes
- •ASA Classes I,II and III patients
- •Patients posted for upper limb surgery below shoulder.
排除标准
- •1.Patient refusal
- •Coagulopathy
- •History of allergy to local anesthetics
- •Infection at the site of block
- •Neurodeficit involving brachial plexus
- •Pregnant women
- •Patients with psychiatric behavior
- •ASA Class IV patients 9.Obese patients BMI>35kg/m2.
结局指标
主要结局
To compare the onset of sensory & motor block
时间窗: One year
次要结局
- •To compare the duration of analgesia •To compare the requirement of rescue analgesic in the postoperative period • To compare the side effects (if any)(One year)