Systolic Time Intervals a Pronostic Tool of Heart Failure in Emergency Departement
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 642
- 试验地点
- 1
- 主要终点
- compare the STIs prognostic performance against clinical scores
研究概览
简要总结
The performance of STIs and clinical scores alone and their combination to predict short term prognosis of acute decompensated heart failure.
详细描述
Acute heart failure is a leading cause of hospitalization and death.Prediction of these adverse events is still challenging.
STI is an old technique based on the recording of two parameters: electrocardiogram and phonocardiogram, and from them measuring the different systolic intervals:
pre-ejection period (PEP),electro-mechanic activation time (EMAT), Left ventricular ejection time (LVET) and systolic time ratio (RTS) were measured.
The aim of these study is to demonstrate whether systolic time intervals (STIs) can improve clinical scores EFFECT (Enhanced Feedback for Effective Cardiac Treatment) and GWTG-HF (Get With the Guidelines-Heart Failure) for predicting 30 day mortality and readmission in patients with acute decompensated heart failure (ADHF) in the ED.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •non traumatic dyspnea
- •age more than 18 years old.
排除标准
- •ECG diagnostic for acute myocardial infarction
- •ischemic chest pain within the prior 24 hours
- •history of a heart transplant
- •pericardial effusion
- •chest wall deformity suspected of causing dyspnea
- •shock,Mechanical Ventilation, vasopressor drugs
- •arrhythmia serious and sustained,
- •pace maker
- •severe mitral valve disease,
- •severe pulmonary arterial hypertension
- •renal failure with creatinine >350micromol/l
结局指标
主要结局
compare the STIs prognostic performance against clinical scores
时间窗: 30 days
the area under ROC curve of the Systolic Time Intervals compared to the one of the EFFECT and GWTG HF scores
次要结局
- compare the STI prognostic performance between HFpEF and HFrEF patients(30 days)
研究者
Pr. Semir Nouira
Professor
University of Monastir