NL-OMON56884尚未招募不适用
Flow versus Volume Controlled Ventilation in intubated obstructive and asthmatic patients - FCV vs VCV in obstructive and asthmatic patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- 18 years or older;
- •- Provided written informed consent;
- •- Undergoing controlled mechanical ventilation via an endotracheal tube;
- •- Reason for intubation being exacerbation of asthma or COPD;
- •- Intubated <=72 hours
排除标准
- •- Severe sputum stasis or production requiring frequent bronchial suctioning
- •(more than 5 times per nurse shift)
- •- Untreated pneumothorax (i.e. no pleural drainage)
- •- Hemodynamic instability defined as a mean arterial pressure below 60mmHg not
- •responding to fluids and/or vasopressors or a noradrenalin dose >0.5mcrg/kg/min
- •- High (>15 mmHg) or instable (an increase in sedation or osmotherapy is
- •required) intracranial pressure
- •- An inner tube diameter of 6mm or less
- •- Anticipating withdrawal of life support and/or shift to palliation as the
- •goal of care
- •- Inability to perform adequate electrical impedance tomography (EIT)
- •measurements with, e.g.:
- •o Have a thorax circumference inappropriate for EIT-belt
- •o Thoracic wounds, bandages or deformities preventing adequate fit of EIT-belt
- •o Recent (<7 days) pulmonary surgery including pneumonectomy, lobectomy or lung
- •transplantation
- •o ICD device present (potential interference with proper functioning of the EIT
- •device and ICD device)
- •o Excessive subcutaneous emphysema
- •- Contra-indications for nasogastric tube or inability to perform adequate
- •transpulmonary pressure measurements with, e.g.:
- •o Recent esophageal surgery
- •o Prior esophagectomy
- •o Known presence of esophageal varices
- •o Severe bleeding disorders
研究者
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