Breakfast for Young Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Energy consumption on test days
研究概览
简要总结
Investigators will in a crossover study test the health effects of eating a dairy-based protein-rich breakfast, isocaloric carbohydrate-rich breakfast or no breakfast in young overweight women. Determination of satiety and hunger using visual analog scores (VAS), collection of blood samples and 2x 24 hours food logs will be collected.
详细描述
This study is a single-blind randomized Cross-Over trial with 30 women aged 18-30 years, each completing three trials. Participants will consume either dairy-based protein-rich breakfast, isocaloric, fiber matched, fat matched, carbohydrate-rich breakfast or no breakfast in randomized order. Three hours later a standardized ad libitum lunch will be served.
Blood samples will be collected (pre, 10 min, 30 min, 60 min, 120 min, 175 min after breakfast) and VAS rating hunger, satiety and desire to eat will be determined (pre, during breakfast, 10, 30, 60, 90, 120, 180 min, during lunch, after lunch). Twenty-four hour food logs on the day before the test day and on the test day will be collected.
Participants will be characterized by determining height (cm), weight (kg), and body composition by a dual-energy X-ray (DXA) scan before the first test day.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Body mass index > 25
- •Age 18-25 years
- •Regular exercise < 5 hour per week
排除标准
- •illness and use of medication affecting the study outcomes
- •allergy towards lactose or gluten
- •weightloss/gain >5kg the last 6 months
- •eating disorder
- •pregnancy
- •breast feeding
- •unable to speak and understand danish
结局指标
主要结局
Energy consumption on test days
时间窗: 0-24 hours
Total energy consumption on test days (24 hour food log)
次要结局
- Change in hunger(0-3 hours)
- Change in satiety(0-3 hours)
- change in desire(0-3 hours)
- Change in leptin(0-3 hours)
- Change in glucagon(0-3 hours)
- Change in glucose-dependent insulinotropic polypeptide (GIP)(0-3 hours)
- Change in ghrelin(0-3 hours)
- Change in Peptide YY (PYY3-36)(0-3 hours)
- Change in insulin(0-3 hours)
- Change in glucose(0-3 hours)
- Energy consumption the day before a test day (food registration)(0-24 hours)