Comparison of Extent of Epidurography and Thoracic Epidural Pressure in the Prone and Lateral Decubitus Position
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Epidural pressure
研究概览
简要总结
It is reported that the distribution of contrast medium had an obvious correlation with the extent of sensory analgesia after injection of LA. Our previous study showed that different posture (prone vs. lateral decubitus) resulted in different degree of contrast medium spread. We supposed that differences of epidural pressure between diverse postures might be one factor contributing those differences of epidurography.
This study was designed to compare the epidural pressure and extent of spread of epidurography between prone and lateral decubitus position
详细描述
It is known that postoperative pain after thoracotomy or lobectomy is very severe, therefore, intraoperative or postoperative pain management using continuous thoracic epidural catheterization is suggested good option to prevent this potential complication.
The spread of local anesthetics is influenced by various factors including volume, location of needle insertion, speed of injection, patient position, age, weight and height. However, there are few studies about the effect of different patient position affeting the epidural pressure and the extent of spread of contrast medium during thoracic epidural catheterization.
Studies of lumbar epidural blockade have shown that lateral position can produce 0-3 segment more to the dependent position compared to the supine position. When the same amount of local anesthetic was injected in supine of sitting position, the most cephalad level of spread was indifferent. Recent studies showed that neck flexion demonstrated significant cephalad spread of contrast dye in high thoracic epidural blockade. The purpose of this study was to compare and evaluate the changes of epidural pressure with extent of spread of contrast medium between different posture
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •lung cancer
- •liver cancer
- •stomach cancer
- •pancreas cancer
排除标准
- •coagulopathy
- •infection
- •previous spine fusion at thoracic level
研究组 & 干预措施
Active Comparator: supine position
Active Comparator: supine position thoracic epidural catheterization with supine position
干预措施: thoracic epidural catheterization (Procedure)
Active Comparator: flexed lateral position
Active Comparator: flexed lateral position thoracic epidural catheterization with flexed lateral position
干预措施: thoracic epidural catheterization (Procedure)
结局指标
主要结局
Epidural pressure
时间窗: 15 minutes after the completion of the intervention
Epidural pressure (mmHg) measurement using pressure transducer between different posture
次要结局
- Contrast dye assessment(5 minutes after the completion of the intervention)
研究者
Ji Hee Hong
Professor
Keimyung University Dongsan Medical Center