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临床试验/NCT04253470
NCT04253470已完成不适用

The Neverending Debate on Progesterone Elevation: Possible Solutions

Istituto Clinico Humanitas1 个研究点 分布在 1 个国家目标入组 8,000 人开始时间: 2012年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
8,000
试验地点
1
主要终点
Impact of PE on CPR and LBR

研究概览

简要总结

The association between serum progesterone (P) levels, measured on the day of ovulation trigger, and the outcome of in vitro fertilization cycles, has been one of the major controversies in the field of ovarian stimulation endocrinology.

This is a single-center retrospective cohort study. Study duration period is from January 2012 to December 2016.

All fresh embryo transfer (ET) both at cleavage stage and blastocyst stage, performed in Humanitas Fertility Center during the study period, were included.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • All fresh embryo transfers both at cleavage stage (Day 2 and Day3) and blastocyst stage (Day 5)
  • Thawed embryo transfer deriving from supernumerary embryos cycles, by P increase, by OHSS, by other reasons (i.e inadequate endometrium, medical complications, etc)

排除标准

  • thawed embryo transfers deriving from PGTA.

结局指标

主要结局

Impact of PE on CPR and LBR

时间窗: January 2012-December 2016

To evaluate the impact of premature high serum P levels on the outcome of fresh embryo transfer cycles in terms of Clinical Pregnancy Rates (CPR) and Live Birth Rates (LBR).

次要结局

  • Blastocyst embryo transfers' outcomes in PE(January 2012-December 2016)

研究者

发起方
Istituto Clinico Humanitas
申办方类型
Other
责任方
Sponsor

研究点 (1)

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