The Neverending Debate on Progesterone Elevation: Possible Solutions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 8,000
- 试验地点
- 1
- 主要终点
- Impact of PE on CPR and LBR
研究概览
简要总结
The association between serum progesterone (P) levels, measured on the day of ovulation trigger, and the outcome of in vitro fertilization cycles, has been one of the major controversies in the field of ovarian stimulation endocrinology.
This is a single-center retrospective cohort study. Study duration period is from January 2012 to December 2016.
All fresh embryo transfer (ET) both at cleavage stage and blastocyst stage, performed in Humanitas Fertility Center during the study period, were included.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 45 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All fresh embryo transfers both at cleavage stage (Day 2 and Day3) and blastocyst stage (Day 5)
- •Thawed embryo transfer deriving from supernumerary embryos cycles, by P increase, by OHSS, by other reasons (i.e inadequate endometrium, medical complications, etc)
排除标准
- •thawed embryo transfers deriving from PGTA.
结局指标
主要结局
Impact of PE on CPR and LBR
时间窗: January 2012-December 2016
To evaluate the impact of premature high serum P levels on the outcome of fresh embryo transfer cycles in terms of Clinical Pregnancy Rates (CPR) and Live Birth Rates (LBR).
次要结局
- Blastocyst embryo transfers' outcomes in PE(January 2012-December 2016)
