IRCT20200408046990N11已完成2 期
Evalution of oral nano-curcumin formulation efficacy in prevention of cisplatin induced nephrotixicity in cancer patients
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 60 years（—）
- 性别
- All
入选标准
- •Patients with cancer and candidates for chemotherapy with regimen containing cisplatin at a dose of 70mg/m2 every three weeks or 40mg/m2 weekly Patient age above 18 years and below 70 years GFR>60 ml/min At the start of chemotherapyNormal liver function Normality of patients' CBC
排除标准
- •Allergy to curcuminPatient dissatisfactionReduction of patient's GFR below 45ml/min during treatmentReceiving other nephrotoxic drugs such as aminoglycosides, amphotericin, vancomycin Patients with chronic heart failure EF<60%Patients with untreated hypothyroidism or hyperthyroidismPatients with active infectionReceiving anti-inflammatory and antioxidant drugs at the same timeUnfavorable health status (PS<70%) based on karnofsky index
研究者
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