Establishment of Ideal IV Sedative Regimen for Successful Fiberoptic Bronchoscopy in Assessing the Site, Severity of Sleep Apnea Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- Desaturation rate
研究概览
简要总结
Venous thromboembolism(VTE) is the third most common cardiovascular complication among hospitalized patients, and can even cause death. VTE often occurs in intensive care patients and there had been many efforts to prevent such complication. The American College of Chest Physicians (ACCP) had published evidence-based clinical practice guideline for VTE prophylaxis.
This study focuses on how VTE prophylaxis is being performed in both medical and surgical ICUs in a single University hospital, and sees the differences in such prophylactic patterns.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •20-60 years old patients with ASA class I-II
- •Scheduled for drug induced sleep endoscope after diagnosed with sleep apnea syndrome
排除标准
- •Patients having hearing difficulties, taking any CNS related medication, history of any adverse drug reaction, Glasgow coma scale < 15
- •Patients with severe cardiopulmonary dysfunction
- •Patients refusal
研究组 & 干预措施
dexmedetomidine 0.5 mcg/kg/hr
干预措施: dexmedetomidine infusion rate, 0.5 mcg/kg/hr (Drug)
dexmedetomidine 1.0 mcg/kg/hr
干预措施: dexmedetomidine infusion rate, 1.0 mcg/kg/hr (Drug)
结局指标
主要结局
Desaturation rate
时间窗: Baseline from 5 min after remifentanil TCI start, 10 min after dexmedetomidine loading start, every 5 min until surgeon can do endoscopy successfully, to immediately after endoscopy
SpO2 \< 90% (checked by pulse oximetry)
次要结局
未报告次要终点