Pattern of Prescribing Anticoagulants As DVT Prophylaxis in Intensive Care Unit of Tertiary Hospital
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- DVT
- Sponsor
- Ain Shams University
- Enrollment
- 400
- Locations
- 1
- Primary Endpoint
- Padua score for medical patients
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Hospitalized patients are at high risk of venous thromboembolism (VTE), and the appropriate use of thromboprophylaxis can significantly reduce the incidence of VTE in high-risk patients. We investigated the pattern of VTE prophylaxis administration among elderly medical patients and assessed its appropriateness based on the American College of Chest Physicians (ACCP) recommendations. Methods A cross-sectional single-center study will be conducted between July 2024 and December 2024, including hospitalized (> 48 h), (≥ 60 years), medical and surgical patients, and excluding patients receiving anticoagulant for other reason, having contraindication to thromboprophylaxis, or had VTE diagnosed within 48 h. The Padua and caprine prediction scores will be used to determine the patients' risk for VTE, and thromboprophylaxis use will be assessed against the ACCP recommendations.
Investigators
Sarah Sabry Hashem
Clinical Pharmacy Associate Professor
Egyptian Chinese University
Eligibility Criteria
Inclusion Criteria
- •Patient records
- •admitted to the ICU with
- •medical or surgical causes
- •recieved anticoagulants for DVT prophylaxis
Exclusion Criteria
- •Patients already on anticoagulant therapy,
- •had history of previous DVT,
- •had End-stage liver disease,
- •admitted with hemorrhage/bleeding
- •not prescribed DVT prophylaxis
Outcomes
Primary Outcomes
Padua score for medical patients
Time Frame: within 24 hours of ICU admission
Venous thromboembolism Risk assessment (Scores 0-3 are low risk and do not warrant prophylaxis. Scores ≥4 are high risk for VTE and subsequent complications; recommendation for thromboprophylaxis.)
Caprini score for surgical patients
Time Frame: within 24 hours of ICU admission
Venous thromboembolism Risk assessment (Total score of 0-1: Low risk of VTE Total score of ≥3: High/moderate risk of VTE )
Secondary Outcomes
- Adverse drug reaction cost(within 24 hours of ICU admission till ICU discharge (at least 48 hours))
- Bleeding risk assessment(within 24 hours of ICU admission)
- Direct Anticoagulant cost(within 24 hours of ICU admission till ICU discharge(at least 48 hours))