NCT00793832已完成不适用
The Effect of Supervised Cardiorespiratory Endurance Exercise Training on Physical Fitness and Energy Expenditure in Roun-en-Y Gastric Bypass and Gastric Banding Surgery Patients.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 主要终点
- Exercise at a level sufficient to accumulate at least 2000kcal per week
研究概览
简要总结
It is hypothesized that the patients in the EXDA group will be able to complete a structured exercise program at a level sufficient to accumulate at least 2000 kcal per week, and that the structured endurance activity will increase their physical fitness and total daily energy expenditure compared to the DA group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •RYGB or GB surgery patients who are at least 12 weeks post surgery
- •BMI of 40 or more
- •age 18-70years
- •sedentary lifestyle (energy expenditure of <35 kcal/kg/day measured by 7-day physical activity recall and no regular moderate physical activity exceeding 20 min/day within the previous 3 months)
- •willingness to alter physical activity in accordance with the intervention programs
- •English or Spanish speaking.
排除标准
- •body weight > 180 kg
- •cardiovascular disease
- •pulmonary disease
- •uncontrolled hypertension (resting DBP >100 or SBP >180 mm of Hg)
- •visual or hearing impairment
- •functional limitations (difficulty walking one-quarter mile or climbing 10 stairs)
- •abnormal ECG on VO2max test ( >1 mm ST segment depression at < 5 METS or with symptoms such as atrial fibrillation, complex ventricular arrhythmias and 3rd degree atrioventricular block)
- •known liver disease due to causes other than nonalcoholic steatohepatitis (liver transaminases > 2.5 times the upper limits of normal [SGPT>105 U/L, SGPT>120 U/L] or total bilirubin >1.5 mg/dL)
- •hematocrit of less than 30%
- •current alcohol abuse (>7 drinks or 210 g/wk for women and >14 drinks or 420 g/wk for men)
- •recreational drug abuse
- •current use of any drugs capable of inducing weight loss (e.g., orlistat, sibutramine, topiramate, etc.)
- •major neuro-psychiatric illnesses impeding competence or compliance
- •pregnancy and lactation
- •chronic renal insufficiency (serum creatinine > 2 mg/dL)
- •untreated thyroid disorders such as hypothyroidism and hyperthyroidism; and 17) bariatric surgical complications including anastomotic leak, wound complications, thrombotic disorders, intestinal obstruction, stomal complications, GI bleeding, recurrent severe abdominal pain, bilious vomiting.
结局指标
主要结局
Exercise at a level sufficient to accumulate at least 2000kcal per week
时间窗: 12 weeks
次要结局
- To compare body weight and composition, quality of life, fasting lipids and lipoproteins, and glycemic control between the two groups.(12 weeks)
研究者
Abhimanyu Garg
Professor
University of Texas Southwestern Medical Center
相似试验
已完成
不适用
The effects of exercise based on cadiopulmonary exercise training (CPX) in depression and exploring the mechanisms involved in the effects on PBMC mitochondria of depressiomajor depressive disorder, persistent depressive disorderJPRN-UMIN000025431Hokkaido University15
已完成
2 期
EXTEND Exercise TrialNon-metastatic, Hormone naïve Prostate CancerNCT02256111Duke University26
进行中（未招募）
不适用
Using Exercise-testing to Explore Patient Differences in Severe AsthmaAsthmaNCT05733143Queen's University, Belfast64
已完成
不适用
The Influence of Different Training Regimens on Electrical Stability Following Myocardial InfarctionIschemic Heart DiseaseCongestive Heart FailureNCT01912690Hadassah Medical Organization60
招募中
不适用
To determine the effect of 12 weeks of selective plyometrics training in addition to their regular cardio-respiratory endurance training on 800 meter running performance in collegiate athletes.CTRI/2020/02/023502Pravara Institute of Medical Sciences