Comparison of analgesic effect of different doses of Dexamethasone as an adjuvant to Bupivacaine in ultrasound guided supraclavicular brachial plexus block.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- To evaluate and compare the duration of analgesic effect with two different doses Dexamethasone (8mg Vs 4 mg) as an adjuvant to Bupivacaine in supraclavicular brachial plexus block.
研究概览
简要总结
Comparison of analgesic effect of different doses of Dexamethasone as an adjuvant to Bupivacaine in ultrasound guided supraclavicular brachial plexus block. Aim: To compare the analgesic effect of Dexamethasone 8mg Vs 4mg as an adjuvant to Bupivacaine in ultrasound guided Supraclavicular brachial plexus block. Study design: Prospective, observational, randomised comparative double blinded study. Materials and Methods: thirty six patients will be divided into three groups, 12 patients each. Group D8 will receive bupivacaine 0.5% 20 mL + dexamethasone 8mg 2 mL, group D4 will receive Bupivacaine 0.5% 20 ml + dexamethasone 4mg 1ml+ 1ml NS and group B will receive 20 ml Bupivacaine + 2ml NS. We will compare the onset of sensory and motor blocks, duration of analgesia and incidence of complications.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 & 2 Ortho upper limb surgeries.
排除标准
- •Patient refusal to participate in study.
- •History of allergy to local anesthetic and Dexamethasone.
- •History of usage of corticosteroids, opioids and any other analgesics.
- •Infection at the site of injection.
- •Pregnant females.
- •Significant cognitive or psychiatric history.
- •History of endocrine disease- Diabetes mellitus and thyroid disease History of CNS, cardiovascular and renal disease.
结局指标
主要结局
To evaluate and compare the duration of analgesic effect with two different doses Dexamethasone (8mg Vs 4 mg) as an adjuvant to Bupivacaine in supraclavicular brachial plexus block.
时间窗: assessment of pain will be done till 20 mins just after giving the block and then in postoperatively at 6 hrs,9 hrs, 12hrs and 24hrs.
次要结局
- To evaluate and compare the time required with respect to achieve:(complete onset of sensory block)