NCT01325844已完成不适用
The Effects of Epidural Anesthesia on the Bioavailability of Nitric Oxide and Renal Function in Patients Undergoing Laparoscopic Surgery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- blood pressure with heart rate variability
研究概览
简要总结
This study was designed to investigate the effects of epidural anesthesia combined with general anesthesia during laparoscopic surgery. The investigators hypothesized that epidural anesthesia will effectively block the activation of the sympathetic nervous system during surgery, thus activating nitric oxide and reducing splanchnic ischemia and decrease in postoperative renal function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •ASA class 1 or 2 adult patients scheduled for endoscopic prostatectomy
排除标准
- •Patient refusal
- •Patients on diuretics
- •Patients with renal failure (eGFR < 60 ml/min/1.73 m2)
结局指标
主要结局
blood pressure with heart rate variability
时间窗: 10 minutes after anesthesia induction
次要结局
未报告次要终点
研究者
研究点 (2)
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