Outcomes of Radical Debridement Versus no Debridement Under Different Surgical Procedures for the Treatment of Thoracic and Lumbar Spinal Tuberculosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 74
- 主要终点
- blood loss in milliliter
研究概览
简要总结
Whether radical debridement is necessary for the treatment of thoracic and lumbar tuberculosis is still questionable. The objective of this prospective randomized study was to compare the outcomes of radical debridement versus no debridement under different surgical procedures for the treatment of thoracic and lumbar tuberculosis.
详细描述
Seventy-four thoracic and lumbar tuberculosis patients with a neurological function of grade D and E underwent surgeries from January 2009 to January 2014. All patients were divided into group A and group B by taking the drawing of lots. In group A, radical debridement, bone graft and instrumentation were performed. In group B, isolated posterior instrumentation without debridement were performed in all cases and drainage of iliopsoas abscess via laparoscopy in 2 cases. The operative time, blood loss, visual analogue score (VAS), erythrocyte sedimentation rate (ESR), kyphotic angle, Frankel grading, fusion rate and complications were evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 67 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Frankel grading was grade D and E
- •Severe back pain
- •Abscess combined with high pressure symptoms
- •Larger sequestrum formation or sinus
- •Significant spinal instability.
排除标准
- •Frankel grading was grade A,B and C
- •Conservative treatment
结局指标
主要结局
blood loss in milliliter
时间窗: 5 years
The operative time in minutes
时间窗: 5 years
erythrocyte sedimentation rate (ESR) in mm/h
时间窗: 5 years
kyphotic angle in degree
时间窗: 5 years
次要结局
未报告次要终点
研究者
Qian Jun
Principal Investigator
The Second Hospital of Anhui Medical University