Diagnostic utility of lung ultrasound in predicting the surfactant therapy for preterm infants
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To determine the diagnostic accuracy of lung ultrasound score in predicting the need for first dose of surfactant therapy in preterm infants (34weeks) with respiratory distress.
研究概览
简要总结
This study is being taken up to predict the the diagnostic accuracy of neonatal lung USG score as a lone marker for evaluating the need for surfactant administration in preterm infants with respiratory distress. We hypothesize that since LUS score reflects lung aeration, it will correlate with requirement of surfactant in preterm babies with respiratory distress. In future, it can prove to be an accurate and early predictor for the need for surfactant therapy in this cohort, thus, allowing timely treatment and as low as reasonably achievable (ALARA) radiation exposure.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 0.00 Day(s) 至 1.00 Day(s)（—）
- 性别
- All
入选标准
- •< 34 weeks neonates admitted to NICU within 6 hours of life with respiratory distress.
排除标准
- •>34 weeks
- •No respiratory distress
- •Admission beyond 6 hours of life to NICU.
结局指标
主要结局
To determine the diagnostic accuracy of lung ultrasound score in predicting the need for first dose of surfactant therapy in preterm infants (34weeks) with respiratory distress.
时间窗: 6 hours
To determine the diagnostic accuracy of lung USG score in predicting the need for second dose of surfactant therapy in preterm infants(34 weeks) with respiratory distress, if indicated clinically
时间窗: 6 hours
次要结局
- To determine the change in LUS score after six hours of surfactant therapy(six hours after surfactant first dose)
- To determine the distribution of LUS score with corresponding oxygen saturation to fraction oxygenation ratio (S/F)(admission)
- To determine the distribution of LUS score with corresponding arterial/alveolar oxygenation ratio (PaO2/PAO2)(at admission)
- To determine the distribution of LUS score with corresponding chest x-ray (CXR)-based classification of RDS as mild, moderate and severe RDS(admission)