Effectiveness of peripheral nerve blocks in acute radicular pain due to lumbar intervertebral disc herniation and its effect on inflammatory cytokines: A prospective cohort study

AIIMS Rishikesh0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1.Age between 18-50 years of both sexes.
•2.History of segmental low back pain of lumbar (L5) or sacral (S1) origin with radiation to unilateral lower limb below knee of less than 1-month duration.
•3.Patients who are not the candidates for surgery.
•4.Average pain score of >=4 on an 11-point NRS.
•5.Tenderness over the concordant peripheral nerves (Gore sign +)
•6.Magnetic resonance imaging (MRI) evidence of nerve root pain concordant with the side and level of clinical features.

•1.Coagulopathy and/or patients on anticoagulants.
•2.Infection at the site of injection.
•3.Hypersensitivity to local anesthetic agent.
•4.Evidence of significant progressive sensory or motor deficit, cauda-equina syndrome, H/O trauma, infection and cancer (Red flag signs).
•5.Evidence of severe psychiatric illness.
•6.History of previous backs surgery/epidural steroid injection.
•7.History of any major comorbid medical conditions, those interfere with recording of study outcomes (any auto-immune diseases), multiple sclerosis, and pregnancy.

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