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临床试验/NCT07602738
NCT07602738已完成3 期

Evaluation of Liquorice Nanogel Versus Diode Laser as an Adjunctive Treatment for Patients With Periodontitis Stage Ⅲ.

Al-Azhar University1 个研究点 分布在 1 个国家目标入组 27 人开始时间: 2024年7月1日最近更新:
适应症

试验速览

阶段
3 期
状态
已完成
入组人数
27
试验地点
1

研究概览

简要总结

Evaluation of the effect of liquorice nanogel versus diode laser on periodontitis stage Ⅲ clinically and microbiologically by molecular analysis of porphyromonas gingivalis using real time PCR.

详细描述

Quantitative analysis technique using real time pcr (polymerase chain reaction) was done to detect presence of porphyromonas gingivalis. Pocket depth (PD), Plaque index (PI), gingival index (GI) and Clinical attachment level (CAL) were measured before work and after 3 months postoperatively.

Analysis was made from gingival crevicular fluid samples of the patients using gutta percha paper points.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patient had Periodontitis stage III with pocket depth ≥ 6mm; indicated for periodontal surgery or CAL ≥ 5mm.
  • Patient agreed to the surgical procedure and clinical trial.
  • Age ranged between 18-50 years old.

排除标准

  • 1: No previous drug was taken affecting bone metabolism. 2- Smoking. 3- Pregnant women and women with menopause. 4- Patients with psychological problems . 5- Patients with abnormal habits. 6- Patients with medical conditions as Diabetes or Hypertension.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alaa Yousri Mohamed

Master Candidate of Oral and Dental Medicine and Periodontology Al Azhar University for girls

Al-Azhar University

研究点 (1)

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