NL-OMON56946尚未招募不适用
Multiomics in systemic inflammation driven brain aging in humans - UNCOVERS
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Planned for elective thoraco-abdominal aortic aneurysm repair that also have an
- •ELD as part of their routine clinical care at Radboudumc
排除标准
- •- Disease states associated with a state of neuroinflammation: brain or spinal
- •surgery within the last 6 months, meningitis or brain infection within the last
- •6 months, presence of a CSF catheter or shunt, presence of known brain tumor,
- •brain injury (e.g., stroke, or subarachnoid hemorrhage) within the last 12
- •months, moderate-severe brain trauma in previous medical history, chronic
- •active alcoholism or substance use.
- •- Pre-existing dementia or neurodegenerative disease
- •- Cognitive impairment interfering with the ability to understand informational
- •study material.
- •- Chronic (>2 weeks) use of immunosuppressive agents (see table 3.3.A, below)
- •- Concomitant diseases resulting in severe immunosuppression (e.g., HIV,
- •hematological malignancies)
- •- Patients that do not speak Dutch or analphabetic patients.
研究者
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