ITMCTR2100004406招募中1 期
Effect of electroacupuncture combined with tACS on working memory and executive function in patients with mild cognitive impairment and its mechanism
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine affiliated to Shanghai University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 50 至 85（—）
- 性别
- All
入选标准
- •1. Patients meeting the core clinical diagnostic criteria of MCI;
- •2. Patients with age >= 50 years old and <= 85 years old are not limited in gender;
- •3. The subjects of Mini Mental State Scale: 18-19 for illiteracy, 21-22 for primary school, 25-27 for middle school and above;
- •4. Montreal Cognitive Assessment Scale score: low education (education years <= 12 years) 19-25 points, higher education (education years > 12 years) 19-26 points indicate mild abnormality.
- •5. Patients with clinical dementia rating scale score <= 0.5 showed no dementia or suspected dementia;
- •6. Patients with no obvious disorder of activities of daily living according to Barthel index;
- •7. Subjects with GDS <= 6 showed no depression;
- •8. Subjects who can tolerate 3 hours of assessment and intervention;
- •9. The subjects who voluntarily participated in this study and signed the informed consent.
排除标准
- •1. Patients with local skin infection, ulcer scar or over sensitivity to acupuncture;
- •2. Patients with severe hemorrhagic diseases and coagulation disorders;
- •3. Patients with a history of epilepsy or seizures; first degree relatives have a history of epilepsy
- •4. Patients with metal implants in the body or head (except stomatology); patients with implanted pacemaker defibrillator and cochlear implant drug pump; patients with implanted pacemaker defibrillator and cochlear implant drug pump;
- •5. Patients with recurrent headache who have no response to drug treatment due to unknown reasons;
- •6. Patients with skull fracture and / or severe head injury; history of head and / or brain surgery;
- •7. Patients with severe heart disease and increased intracranial pressure;
- •8. Patients taking tricyclic antidepressants, antipsychotics and other drugs to reduce seizure threshold;
- •9. Patients with other diseases or history affecting cognitive function;
- •10. Patients with depression, schizophrenia and other mental diseases;
- •11. Pregnant or lactating women.
研究者
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