临床试验/NCT03021538

NCT03021538终止不适用

Randomized Clinical Trial of Intraoperative Extracorporeal Membrane Oxygenation (ECMO) Versus Cardiopulmonary Bypass (CPB) in Lung Transplantation

The Cleveland Clinic1 个研究点分布在 1 个国家目标入组 13 人开始时间: 2017年4月17日最近更新: 2020年3月24日

适应症

试验速览

阶段: 不适用
状态: 终止
发起方: The Cleveland Clinic
入组人数: 13
试验地点: 1
主要终点: Need for Blood Transfusion

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study seeks to compare outcomes of 2 different methods of cardiopulmonary support during lung transplant surgeries.

详细描述

This study will compare use of extracorporeal membrane oxygenation (ECMO) and heart-lung bypass (CPB) during lung transplant procedures and their short and long term outcomes.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•The study population will be all patients requiring cardiopulmonary support while undergoing lung transplantation at our institution.

排除标准

•Patients undergoing concomitant cardiac operations with indication for obligate use of cardiopulmonary bypass
•Patient with specific anatomy that require full cardiac decompression such as severe pulmonary hypertension or large heart that are shifted severely into the left chest
•Patients with high likelihood of significant pleural bleeding that will require returning the blood back into the cardiotomy reservoir
•Patients bridged to transplant with ECMO
•Cystic fibrosis/bronchiectasis/resistant infection patients where surgeon will need to remove both lungs prior to implantation
•Patients who the surgeon feels would be better served with CPB rather than ECMO- These patients will be entered into a registry and followed.

结局指标

主要结局

Need for Blood Transfusion

时间窗: 72 hours after surgery

Number of pRBC transfusion that resulted due to postoperative bleeding

次要结局

未报告次要终点

研究者

发起方

The Cleveland Clinic

申办方类型

Other

责任方

Principal Investigator

主要研究者

Michael Zhen-Yu Tong, MD

Cardiac Surgeon

The Cleveland Clinic

研究点 (1)

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