The Effect of Flow-controlled Ventilation on Hemodynamic and Respiratory Parameters in Laparoscopic Surgeries, Prospective Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- effects of flow controlled ventilation on arterial pressure
研究概览
简要总结
It is aimed to investigate the effect of flow controlled ventilation on intraoperative respiratory parameters and hemodynamic parameters in laparoscopic operations.
详细描述
Study will begin after ethics committee approval and the patient's written and verbal consent .
Prospective observational studies will be conducted on patients over the age of 18 who will undergo laparoscopic surgery in the operating rooms. Patients who did not give verbal and written consent, emergency interventions, patients at risk of aspiration, patients with an ASA physical status above 3 and a diagnosis of COPD will be excluded.
Patients will be randomized and divided into two groups. Patients intraoperatively ventilated with a conventional ventilator (GE™ Avance™ CS2, VCV mode) Group 1, intraoperative ventilation Ventinova ( Evone®, Ventinova Medical, Eindhoven, the Netherlands, FCV mode) will be referred to as Group 2. Standard monitoring (ECG; SpO2, end tidal CO2,arterial blood pressure) will be applied to all patients. Anesthesia induction will be performed with propofol, fentanyl, rocuronium bromide as standard; In addition, anesthesia maintenance of the patients will be provided with propofol and remifentanil.
Respiratory parameters such as peripheral SpO2, PaCO2 value, peak airway pressure of each group will be recorded, and intraoperative hemodynamic parameters (systolic, diastolic, mean blood pressure, heart rate) of each group will be monitored and recorded.
Postoperative respiratory functions and length of hospital stay of all patients will be monitored and recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who will undergo laparoscopic surgeries, ASA 1,2,3 physical status
排除标准
- •patients who do not give verbal and written consent, emergency interventions, patients at risk of aspiration, patients with an ASA physical status above 3 and a diagnosis of COPD
结局指标
主要结局
effects of flow controlled ventilation on arterial pressure
时间窗: intraoperatively
Arterial blood pressure in mmHg
effectcs of flow controlled ventiletion on endtidal CO2
时间窗: intraoperatively
endtidal CO2 in mmHg
effects of flow controlled ventilation on mean arterial pressure
时间窗: intraoperatively
mean arterial pressure change in percent
effectcs of flow controlled ventiletion on peak airway pressure
时间窗: intraoperatively
peak airway pressure in cmH2O
effects of flow controlled ventilation on heart rate
时间窗: intraoperatively
heart rate in bpm
次要结局
- respiratory related complications(intraoperative period and postoperative first week)
研究者
Nurseda Dundar
Principal Investigator
Derince Training and Research Hospital