Evaluation of Scanning Laser Polarimetry Findings in Individuals With Exfoliation Syndrome Compared With Normal Controls
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- Scanning laser polarimetry parameters, evaluation of retina nerve fiber layer thickness
研究概览
简要总结
To compare the Retina Nerve Fiber Layer thickness, measured with Scanning Laser Polarimetry in subjects with exfoliation syndrome and normal controls and to evaluate the value of scanning laser polarimetry in the early diagnosis and management of exfoliative glaucoma
详细描述
To compare the Scanning Laser Polarimetry findings in subjects with exfoliation syndrome and normal controls and to evaluate the value of scanning laser polarimetry in the early diagnosis and management of exfoliative glaucoma. Prospective study in progress. The investigators compare and analyze the scanning laser polarimetry parameters in consecutive subjects with exfoliation syndrome and normal intraocular pressure and compared them with consecutive normal controls. Randomly selected patients with exfoliation syndrome and normal controls undergo a comprehensive ophthalmic exam which includes 3 IOP measurements, corneal pachymetry, automated perimetry and assessment of the retina nerve fiber layer with scanning laser polarimetry. The investigators hypothesize that patients with exfoliation syndrome may show worse scanning laser polarimetry parameters than normal controls and this may prove to be an early sign of exfoliative glaucoma development. Evaluation of retina nerve fiber layer thickness may help us in identifying earlier those individuals with exfoliation syndrome that will develop exfoliative glaucoma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Exfoliation material on pupil
- •Intraocular pressure below 21 mm Hg without therapy
- •No glaucomatous damage
- •Age between 60-75
- •Open angle
排除标准
- •Other Ophthalmic diseases
- •Corneal disorders
- •Diabetic Retinopathy
- •Optic Neuropathy (other than glaucomatous neuropathy)
- •Ocular surgery or laser
结局指标
主要结局
Scanning laser polarimetry parameters, evaluation of retina nerve fiber layer thickness
时间窗: Morning measurement (10:00 - 13:00)
次要结局
- Corneal thickness, exfoliation syndrome subjects that will develop exfoliation glaucoma(10:00-13:00)
研究者
AGP Konstas
Professor in Ophthalmology
Aristotle University Of Thessaloniki
