Dissecting the mechanisms of fear formation: a pharmacological study with healthy volunteers - camf

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 120 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

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•The subjects must be in good mental and physical health (as established by first contact and health questionnaire). Participants with a past or present psychiatric,or respiratory (including asthma) will be excluded from the study. Background of high blood pressure or cardiovascular diseases will also be an exclusion criterion. Testing days for female subjects will demand that they are in the end of the follicular phase in order to standardize the influence of gonadal hormones. Participants must be drug and alcohol free from at least 48 hrs before time of testing and should refrain from caffeine and cigarette smoking from 3 hours before testing. Age should be comprised between 18 and 40 years.

•Uncorrected vision disturbances, pregnancy, use of oral contraceptives or lactation, any neurological and psychiatric diseases past and present, including manic and suicidal depression.History of seizures, respiratory disease (including asthma), cardiovascular illness or head trauma with loss of consciousness, abnormal blood pressure, glaucoma or abnormal clinical laboratory tests. Subjects will also be excluded when they cannot understand the Dutch and English languages sufficiently to understand the purposes and implications of the experiment.

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