An Observational study comparing the efficacy of low dose ketamine and paracetamol pretreatment in alleviating pain due to propofol injection.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min
研究概览
简要总结
Propofol short acting intravenous anaesthetic agent is extensively used because of its smooth induction and recovery .Its a agent of choice in day care anaesthesia ,for sedation in ICU,as maintenance agent in anaesthesia.However pain due to this is major drawback.Various strategies have been practiced to reduce pain like choosing a larger vein,cooling propofol,dilution of propofol,increasing speed of injection.
Ketamine and paracetamol are good analgesic properties so in this study comparing between two which provides better pain relief.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anesthesiologists physical status (ASAPS) I and II patients undergoing elective surgeries under general anaesthesia.
排除标准
- •Suspected allergy to propofol,ASAPS 3 and 4,patient refusal,emergency surgeries.
结局指标
主要结局
to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min
时间窗: to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min
次要结局
- to observe for hemodynamic changes if any before administering drug ,after intubation ,5 mins after intubation ,10 mins after intubation(0,5,10 mins)