Evaluation of the Efficacy of Intense Pulse Light Combined With Lipiflow in the Treatment of Meibomian Gland Dysfunction
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 主要终点
- Breakup time
研究概览
简要总结
To compare the effect of IPL combined with lipiflow and IPL combined with meibomian gland massage in treating meibomian gland dysfunction of different degrees ,focusing on effective rate, lasting time and changes of meibomian gland function and morphology.
详细描述
To divide all participants into two groups, group one treated with IPL combined with Lipiflow and group two treated with IPL combined with meibomian gland massage.The following parameters were recorded after treatment: the effective rate, lasting time and changes of meibomian gland function and morphology.All parameters were compared between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with meibomian gland dysfunction
- •patients with ocular discomfort
- •skin type:FitzpatricⅠ-Ⅳ
排除标准
- •patients with acute ocular inflammation
- •eye surgery history in the last 12 months
- •patients who have received IPL or Lipiflow in the last 12 months
- •patients who wear contact lens in last one month
结局指标
主要结局
Breakup time
时间窗: 6 months
the shorter time, the poorer of the tear film stability
ocular surface disease index(OSDI)
时间窗: 6 months
The OSDI is assessed on a scale of 0 to 100,with higher scores representing greater disability
meibomian gland expressibility score and meibum quality score
时间窗: 6 months
The score is on a scale of 0 to 6.The higher scores, the severity of the meibomian gland function(the highest score is 6 and the lowest score is 0)
meibomian gland dropout score
时间窗: 6 months
the higher scores, the severity of the meibomian gland morphology(The highest score is 6 and the lowest score is 0)
次要结局
未报告次要终点