NCT02109705已完成不适用
Porphyromonas Gingivalis - a Responsible Pathogen in Alzheimer's Disease?
University Hospital Muenster1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2014年3月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Cmax Antibody Levels against Gingipains
研究概览
简要总结
With this study the investigators would like to analyze the the role of periodontal disease and especially the role of Porphyromonas gingivalis in initiation and progression of Alzheimer's Disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 40-70
- •caucasian origin
- •dementia (Alzheimer's or other dementia)
- •cognitive healthy (need for spinal anesthesia)
排除标准
- •use of antibiotics within las 6 months
- •pregnancy
- •another illness explaining the symptoms in a better way
- •smoking (>10 cigarettes)
- •patients who have a legal custodian
结局指标
主要结局
Cmax Antibody Levels against Gingipains
时间窗: Baseline
laboratory analysis
次要结局
- Cmax Beta-Amyloid(Baseline)
研究者
研究点 (1)
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