The Effect of a Complete Course of Antenatal Steroids on Mortality and Morbidity of Preterm Infants
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 710
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
The aim is to evaluate the impact of a complete course of antenatal steroids treatment on mortality and main morbidities in a current population of preterm infants.
详细描述
All infants admitted in the Neonatal Department born with less than 32 weeks of gestational age are included.
Data are prospectively recorded. Perinatal variables (Gestational age, materna condition at admission, antenatal steroids treatment, gender and results of histological analysis of the placenta) are recorded as well as respiratory status during hospitalization and morbidities at discharge. Results of neurodevelopment test performed at 24 months of corrected age are also included.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 6 Hours（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All infants admitted in the NICU (with less than 6 hours after birth) born with less than 32+0 weeks of gestational age (GA).
排除标准
- •Congenital malformations.
- •premature infants in whom active resuscitation measures are not established.
结局指标
主要结局
Mortality
时间窗: at hospital discharge, an average of 2-4 months.
次要结局
- Number of participants with Bronchopulmonary dysplasia (BPD) diagnosis.(36 weeks postmenstrual age)
- Number of participants requiring Surfactant administration(in the first 3 days after birth)
- Number of participants that requires Mechanical ventilation.(during hospitalization, and average of 2-4 months)
- Number of participants with Neurodevelopment disability(performed at 24 months)
研究者
Manuel Sanchez Luna
Medical Doctor. Pediatric Profesor
Hospital General Universitario Gregorio Marañon