NCT02721693已完成不适用
COPD, Physical Exercise and Troponin T
LHL Helse2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2016年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Troponin T concentration 3 h
研究概览
简要总结
The primary purpose of the study is to investigate if physical exercise is associated with myocardial damage, expressed by elevated troponin T, in patients with COPD.
详细描述
Patients with COPD will perform a cardiopulmonary exercise test (CPET) on treadmill until exhaustion, 8-12 minutes. Venous blood will be drawn before exercise test and 15 minutes, 3 hours and 24 hours after test for analysis of high sensitive Cardiac troponin T (hs-cTnT). The investigators will also measure arterial bloodgas, oxygen uptake, carbon dioxide consumption, ventilation, blood pressure, ECG, heart rate and ask for dyspnea-score.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BODE-index ≥ 2
- •Referred by physician to a CPET
排除标准
- •Other serious pulmonary diseases (e.g. cancer, sarcoidosis, restrictive pulmonary diseases)
- •Chronic heart disease with unstable angina or myocardial infarction ≤ 3 months prior to inclusion
- •Percutaneous coronary intervention (PCI)
- •Hypertension that is not controlled
结局指标
主要结局
Troponin T concentration 3 h
时间窗: 3 h
次要结局
未报告次要终点
研究者
Anne Helene Edvardsen
Head of Out Patient and Laboratory Department, Researcher
LHL Helse
研究点 (2)
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