High Definition-transcranial Direct Current Stimulation (HD-tDCS) for Stroke Rehabilitation
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
研究概览
简要总结
The purpose of this study is to assess the changes in language processing of patients with chronic aphasia after receiving non-invasive brain stimulation.Previous research using traditional transcranial direct current stimulation (tDCS) using 2 sponge electrodes has shown that persons with aphasia show more improvement after treatment when that treatment is accompanied by brain stimulation. Traditional tDCS has recently been modified to deliver current to more specific locations in the brain. This new delivery method is called high-definition tDCS (HD-tDCS). It is not known whether traditional tDCS (more diffuse current delivery) or HD-tDCS (more focal current delivery) will be the better approach for enhancing treatment outcomes. To answer this question, computerized speech-language treatment will be administered during the application of the different forms of brain stimulation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single
入排标准
- 年龄范围
- 25 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •one-time ischemic stroke in the left hemisphere
- •greater than 6-months post-stroke onset
- •between 25 and 80 years of age
- •aphasia diagnosis (as determined by pre-treatment language-based testing)
- •right-handed (before the stroke)
- •native speaker of English
- •ability to provide informed written or verbal consent
排除标准
- •clinically reported history of dementia, alcohol abuse, psychiatric disorder, traumatic brain injury, or extensive visual acuity or visual-spatial problems
- •factors contraindicative of tDCS administration (sensitive scalp, previous brain surgery)
- •prior history of epileptic or unprovoked seizures occurring during the previous 12 months.