The Role of Lung and Diaphragm Ultrasonography in Predicting Clinical Progression in Patients Receiving High-Flow Nasal Oxygen and Non-Invasive Mechanical Ventilation Support for Hypoxemic Respiratory Failure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 91
- 试验地点
- 2
- 主要终点
- Lung and diaphragm ultrasound evaluation for risk of intubation
研究概览
简要总结
The goal of this observational study is to evaluate whether the risk of intubation in patients with hypoxemic respiratory failure who were monitored in the intensive care unit and received non-invasive mechanical ventilation and high-flow nasal oxygen treatment could be predicted using lung and diaphragm ultrasound.
The main question it aims to answer is:
Can lung and diaphragm ultrasound predict the risk of intubation in patients with hypoxemic respiratory failure?
详细描述
Between January 1, 2024, and May 1, 2024, the diaphragm thickness fraction, excursion, LUS score, ROX index, and the LUSS/ROX index ratio were evaluated using lung and diaphragm ultrasound in 91 patients admitted to the intensive care unit with a diagnosis of hypoxemic respiratory failure. These evaluations were performed at the 6th, 12th, 24th, and 48th hours of their ICU stay, and during intubation if the decision for intubation was made
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •PaO2 <60 mmHg detected in arterial blood gas samples at the time of admission to the intensive care unit
排除标准
- •Under the age of 18
- •History of lung and diaphragm surgery
- •Congenital, acquired or traumatic diaphragmatic hernia
- •Diaphragm paralysis
- •Hemodynamic instability requiring vasoactive drug support
- •Do not agree to participate in the study
结局指标
主要结局
Lung and diaphragm ultrasound evaluation for risk of intubation
时间窗: 48 hours
Lung and diaphragm ultrasound can predict risk of intubation
次要结局
- ROX index evaluation for risk of intubation(48 hours)
- LUSS/ROX index ratio evaluation for risk of intubation(48 hours)
研究者
Simge Evren
Principal Investigator
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization