NCT05835401已完成不适用
Effects of Dietary Nitrate Intake on Cardiovascular Performance in Response to Hand Grip Test in Bodybuilders
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 13
- 试验地点
- 1
- 主要终点
- 1. Values of systolic and diastolic blood pressure (mmHg)
研究概览
简要总结
Through a randomized, crossover, double-blind, placebo-controlled clinical trial, 20 bodybuilders will participate a acute-day trial with two intervention protocols: 1) placebo and 2) nitrate; in which will ingest beet juice with or without NO3 in its composition with a 7-day washout interval.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Anabolic steroid use in the past or actually;
- •Participation at least one bodybuilding competition;
排除标准
- •Previous history of acute myocardial infarction and/or stroke;
- •Allergy or intolerance to nitrate, gluten, or milk;
- •Medications (proton pump inhibitors, beta-blockers, calcium channels antagonists).
结局指标
主要结局
1. Values of systolic and diastolic blood pressure (mmHg)
时间窗: up to 2 years
次要结局
- Plasmatic concentrations of nitrate and nitrite (mmol/L)(up to 2 years)
- Values of heart rate variability (ms)(up to 2 years)
- Values of heart rate (beats per minute)(up to 2 years)
- Values of hand grip strength (kgF)(up to 2 years)
- Plasmatic concentrations of nitrate and nitrite (mmol/L)(up to 2 years)
- Values of heart rate variability (ms)(up to 2 years)
- Values of heart rate (beats per minute)(up to 2 years)
- Macrovascular function (Flow mediated dilatation%)(up to 2 years)
- Values of hand grip strength (kgF)(up to 2 years)
研究者
Cicero Jonas R Benjamim
Principal investigator
University of Sao Paulo
研究点 (1)
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