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临床试验/NCT05604703
NCT05604703已完成不适用

Comparison of Two Different Periodontal Disease Classifications At the Patient Level

Kutahya Health Sciences University1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2021年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
300
试验地点
1
主要终点
New periodontal classifıcatıon stage

研究概览

简要总结

Due to some deficiencies in the classification defined by Armitage in 1999, a new periodontal classification was published in 2018. New periodontitis A staging and grading system was used for classification. Staging depends largely on the severity of the disease, while grading is based on the rate of disease progression to the past. It provides additional information on a risk-based analysis and assessment of risk.The aim of this study is to reveal the differences between the old periodontal classification and the new periodontal disease classification published in 2018. Periodontitis in the literature review. The two classifications were compared in patients. However, a study on gingival recession not done. Anamnesis, routine periodontal indices, routine radiographs of 300 patients, first of all According to the 1999 Periodontal Disease Classification, after it will be classified according to the New Periodontal Disease Classification developed in 2018. Thus, two different Periodontal Disease Classifications, old and new, comparison will be made.

详细描述

In the 1999 periodontal disease classification, the diagnosis of chronic and aggressive periodontitis was subdivided into localized and generalized. Chronic periodontitis is an inflammatory disease of supporting tissues followed by pocket formation, gingival recession, periodontal ligament, alveolar bone and attachment loss. Aggressive periodontitis is characterized by rapid periodontal attachment loss and alveolar bone loss in which the patient is systemically healthy, inherited, and the presence of Aggregatibacter Actynomyecetemcomitans in diseased areas.

Due to some deficiencies in the classification defined by Armitage1 in 1999, the need for a new periodontal classification emerged in 2018. These shortcomings are;

  1. There is no specific evidence of pathophysiology that differentiates cases into "aggressive" or "chronic" periodontitis or guides different types of treatment.

2 There is little evidence that aggressive and chronic periodontitis are different diseases. However, there is evidence that multiple factors and their interactions influence clinically observable disease outcomes (phenotypes) at the individual level.

  1. On a population basis, average rates of periodontitis progression are consistent across all populations observed worldwide. However, there is evidence that certain segments of the population exhibit different levels of disease progression.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 99 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • be over 18 years old
  • Patients with recorded periodontal indices and radiographs
  • Patients without disease affecting bone metabolism

排除标准

  • Mentally retarded patients
  • Pregnant and breastfeeding patients
  • Patients receiving radiotherapy
  • Patients who do not use drugs that impair bone metabolism such as bisphosphonates

结局指标

主要结局

New periodontal classifıcatıon stage

时间窗: T0=baseline

Number of patients according to Staging depends on the severity of the disease; clinical attachment loss, amount and percentage of bone loss, probing depth, angular the presence and extent of bone defects and furcation involvement, tooth mobility, and tooth loss. determined by considering the variables.

New periodontal classifıcatıon grade

时间窗: T0=baseline

Number of patients according to Grading is based on the rate of disease progression. It reflects an analysis based on diabetes and varies depending on the HbA1c value if the patient has diabetes, the number of cigarettes smoked, and the bone loss/age ratio.

Number of aggressıve or chronic periodontitis patients according to 1999 armitage periodontal classification

时间窗: T0=baseline

The age and systemic diseases of the patient are learned and the pocket depth, alveolar bone and attachment loss are measured and classified as localized or generalized with aggressive or chronic periodontitis.

次要结局

未报告次要终点

研究者

发起方
Kutahya Health Sciences University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Berceste Guler

Principal Investigator

Kutahya Health Sciences University

研究点 (1)

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