A Retrospective Study on the Practice and Safety of Airway Management in Dutch Emergency Departments
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Different complications of endotracheal intubation
研究概览
简要总结
Describing characteristics of the practice of airway management in Dutch emergency departments, including information about patient demographics, indications, performer characteristics, equipment and medication used and complications due to intubation.
详细描述
Endotracheal intubation can be a lifesaving intervention for critically ill patients in the emergency department (ED). Endotracheal intubation is, however, a high-risk procedure with many potential complications, which seem to be even more prevalent when carried out in the ED compared to for example the operating theater. This is possibly due to multiple reasons such as a sicker population, non-elective setting, a higher variability among indications for intubation or competence of providers.
Internationally, large registries were established and multiple observational studies have been performed to gain more information about the methods, safety and complications of intubations in the ED. While in recent years these studies have added to our knowledge of ED airway management, there is still a lack of high-quality studies and there is a strong argument for increased research. To date, no studies have been published of airway management in Dutch EDs. The investigators therefore have no knowledge about any factors possibly influencing intubation outcomes and complications nor comparability with international data. Among these are factors that have been associated with preventable harm and death and insight into these factors could be used for improvement of the safety of airway management in Dutch EDs.
This study is therefore intended to provide a comprehensive review of the clinical practice and characteristics of endotracheal intubations within Dutch EDs. The results could potentially be used for comparative analysis against global datasets. Additionally, the insights gained from this study will shed light on existing gaps prevalent in the current registration processes of intubations in the Netherlands. Furthermore, these insights could act as a stepping stone for future investigations that can lead to a deeper understanding of the methodologies, safety protocols, and associated complications of endotracheal intubations within Dutch EDs
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients who underwent endotracheal intubation between 01-01-2019 and 31-12-2023 in the participating ED's
排除标准
- •Patients for which no information about the intubation can be found in the electronic patient chart will be excluded from the study.
结局指标
主要结局
Different complications of endotracheal intubation
时间窗: At the time of intervention and consequent 1 hour
* significant decrease of SpO2. Defined as: desaturation of \>10% from baseline or as defined by the treating physician * significant decrease of blood pressure. Defined as: systolic pressure \<90mmHg with a drop of \>20% from baseline or as defined by the treating physician. * significant increase of blood pressure. Defined as: systolic pressure \> 160mmHg with a rise of \>20% from baseline, or as defined by the treating physician. * significant bradycardia. Defined as: heart rate \< 40/min and a drop of \> 20% from baseline, or as defined by the treating physician. * significant tachycardia. Defined as: heart rate \> 160/min and a rise of \> 20% from baseline, or as defined by the treating physician. * dental or airway trauma * oesophageal or mainstem bronchial intubation * vomiting or aspiration * laryngospasm * equipment failure * medication error * cardiac arrest * failed attempt / need for an emergency surgical airway * other
次要结局
未报告次要终点
研究者
Peter Veldhuis
Principal Investigator
Medical Centre Leeuwarden