Cross Sectional Evaluation of Coughing Force in Stroke Patients With Severe Aspiration
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Coughing force
研究概览
简要总结
To assess coughing force during reflex coughing test in those with severe dysphagia and severe aspiration and compare them to than those with stroke patients with no signs of dysphagia/aspiration.
详细描述
Severe aspiration with a compromised cough function can be a risk factor of aspiration pneumonia.
Reflexive coughing can be tested by administration of citric acid via a nebulizer. The objective of this study is to measure the cough force produced via citric acid inhalation challenge, and determine if those with severe aspiration with severe dysphagia have more weak cough force during reflexive cough testing that those post-stroke patients with no signs of aspiration or dysphagia after stroke.
We also aimed to measure the strenght of the respiratory measures with the use of surface EMG.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Confirmed stroke lesions
- •Confirmed aspiration during vfss or fees examinations
排除标准
- •Episode of acute pneumonia or pulmonary embolism at time of enrollment
- •Previous history of chronic respiratory disorders or other systemic disorders that may affect respiratory function ( ex, rheumatoid disease, spinal cord injury)
- •Stroke patients with multiple brain lesions
- •Episode of Diaphragm weakness due to peripheral polyneuropathy or unilateral phrenic nerve palsy
- •Previous episode of abdominal or thoracic surgery within one year of enrollment
- •Concomitant diagnosis of myopathy, muscular dystrophy or other disorders that may affect respiratory muscles.
- •Episode of rib fracture within one year of enrollment
- •Chronic alcoholism
- •Patient with previous diagnosis of dementia or with impaired cognitive function that may limit full participation at the evaluation
- •Patient with tracheostomy state
结局指标
主要结局
Coughing force
时间窗: baseline one time
Coughing force as assessed by reflexive cough test
次要结局
- Coughing force during voluntary coughing(baseline one time)
研究者
Sun Im
Assistant Professor
The Catholic University of Korea