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临床试验/NCT04336995
NCT04336995已完成4 期

Echocardiographic Assessment of Pulmonary Transit Time Following Exercise

Vanderbilt University Medical Center2 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2020年8月27日最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
入组人数
14
试验地点
2
主要终点
Pulmonary Transit Time

研究概览

简要总结

The study seeks to measure pulmonary transit time via contrast-echocardiography before and after exercise.

详细描述

The ability to measure the amount of blood in the lungs using heart-ultrasound (echocardiography) can be useful to estimate how much fluid is in a patient's circulation, which can influence diagnosis and treatment of certain types of heart failure. In some patients, the amount of fluid is normal at rest, but can increase with activity and thus a diagnosis of heart failure can only be made after exercising. Currently, the amount of fluid is measured invasively. We have shown that echocardiography can measure the amount of fluid in the lung circulation at rest without the need for an invasive procedure. We now seek to find out if we can make a similar measurement after exercise. If successful, the need for catheter procedures may be reduced in certain types of heart failure.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years old
  • Able to give informed consent

排除标准

  • Known allergic reaction to Definity or Optison ultrasound contrast
  • Pregnancy/Nursing - as assessed/disclosed by the participant

结局指标

主要结局

Pulmonary Transit Time

时间窗: 3-10 seconds

interval required for the pulmonary blood volume to traverse the pulmonary circulation

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ken Monahan

Assistant Professor of Medicine

Vanderbilt University Medical Center

研究点 (2)

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