Echocardiographic Assessment of Pulmonary Transit Time Following Exercise
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 2
- 主要终点
- Pulmonary Transit Time
研究概览
简要总结
The study seeks to measure pulmonary transit time via contrast-echocardiography before and after exercise.
详细描述
The ability to measure the amount of blood in the lungs using heart-ultrasound (echocardiography) can be useful to estimate how much fluid is in a patient's circulation, which can influence diagnosis and treatment of certain types of heart failure. In some patients, the amount of fluid is normal at rest, but can increase with activity and thus a diagnosis of heart failure can only be made after exercising. Currently, the amount of fluid is measured invasively. We have shown that echocardiography can measure the amount of fluid in the lung circulation at rest without the need for an invasive procedure. We now seek to find out if we can make a similar measurement after exercise. If successful, the need for catheter procedures may be reduced in certain types of heart failure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 years old
- •Able to give informed consent
排除标准
- •Known allergic reaction to Definity or Optison ultrasound contrast
- •Pregnancy/Nursing - as assessed/disclosed by the participant
结局指标
主要结局
Pulmonary Transit Time
时间窗: 3-10 seconds
interval required for the pulmonary blood volume to traverse the pulmonary circulation
次要结局
未报告次要终点
研究者
Ken Monahan
Assistant Professor of Medicine
Vanderbilt University Medical Center
