IRCT2014100719427N1已完成2 期
Effects of intravenous and catheter directed thrombolytic therapy with recombinant tissue plasminogen activator (Alteplase) in non-traumatic acute limb ischemia; a randomized double-blind clinical trial
Vice chancellor of Research, Mashhad University of Medical Sciences0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 75 years（—）
- 性别
- All
入选标准
- •Age 18 to 75 years; symptoms duration of 1 to 14 days; Acute limb ischemia (ALI) of grade IIa and IIb according to the Rutherford classification; absence of distal run off in angiography; Ankle-Brachial Index (ABI) less than 0.8
- •Exclusion criteria: Severe anemia (Hb less than 8 gr per dL); thrombocytopenia (platelet count less than 80000 per micl); low serum fibrinogen (fibrinogen less than 100 mg per dL); severe hypertension (systolic more than 160 mmHg, diastolic more than 100 mmHg); trauma or surgery less than 14 days before intervention; history of subarachnoid hemorrhage; life expectancy of less than 14 months; major internal bleeding less than 6 months before intervention; pregnancy; lumbar puncture 2 weeks before intervention
排除标准
- 未提供
研究者
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