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临床试验/JPRN-UMIN000009105
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Influence of aldehyde dehydrogenase2 genotype on peripheral vasodilation, nitrate tolerance and oxidative stress by organic nitrates: randomized crossover trial - Influence of aldehyde dehydrogenase2 genotype on the effects by organic nitrates

Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University0 个研究点目标入组 80 人开始时间: 2012年10月15日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
80

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
20years-old 至 40years-old(—)
性别
All

入选标准

  • 未提供

排除标准

  • 1. History of cardiovascular disease 2. severe hepatic dysfunction 3. severe renal dysfunction 4. woman who is pregnant or possibly be pregnant 5. History of severe allergy or allergic reaction to nitroglycerin and isosorbide dinitrate 6. History of glaucoma 7. On medical treatment 8. On medical treatment of phosphodiesterase 5 9. Systolic blood pressure <90 mmHg 10. Body weight <40 kg or >90 kg 11. Not appropriate to this study by other reasons

研究者

发起方
Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University

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