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临床试验/NCT01029080
NCT01029080已完成不适用

Dynamic Cerebrovascular Autoregulation During Sepsis and Sepsis-associated Delirium

Johannes Gutenberg University Mainz1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2009年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
Disturbed cerebrovascular autoregulation correlates with sepsis associated delir

研究概览

简要总结

The aim of the study is to correlate the dynamic cerebrovascular autoregulation by patients with sepsis with a sepsis-associated delirium.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • clinical symptoms of sepsis, severe sepsis and septic shock
  • possibility for measurement of transcranial doppler ultrasound
  • age over 18 years

排除标准

  • preexisting cerebrovascular disease
  • preexisting immunological disease
  • traumatic brain injury
  • intracranial infectious disease
  • pregnancy

结局指标

主要结局

Disturbed cerebrovascular autoregulation correlates with sepsis associated delir

时间窗: 1 year

The Index of autoregulation (Mx) was measured and correlated with the clinical incidence of a sepsis associated delir

次要结局

  • Correlation between inflammatory parameters and disturbed cerebrovascular autoregulation(1 year)
  • Correlation between inflammatory parameters and sepsis-associated delirium(1 year)

研究者

发起方
Johannes Gutenberg University Mainz
申办方类型
Other
责任方
Principal Investigator
主要研究者

Patrick Schramm

Senior Physician

Johannes Gutenberg University Mainz

研究点 (1)

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